| Great Wyrley to Spello | 950.70 mi (1,530.00 km) |
| Great Wyrley to Spilamberto | 815.98 mi (1,313.20 km) |
| Great Wyrley to Spilimbergo | 805.23 mi (1,295.89 km) |
| Great Wyrley to Spinea | 807.86 mi (1,300.13 km) |
| Great Wyrley to Spoleto | 963.44 mi (1,550.50 km) |
| Great Wyrley to Spoltore | 1,027.25 mi (1,653.20 km) |
| Great Wyrley to Spresiano | 797.56 mi (1,283.55 km) |
| Great Wyrley to Squinzano | 1,265.85 mi (2,037.19 km) |
| Great Wyrley to Statte | 1,229.55 mi (1,978.76 km) |
| Great Wyrley to Stezzano | 714.12 mi (1,149.26 km) |
| Great Wyrley to Strada | 875.44 mi (1,408.88 km) |
| Great Wyrley to Stradella | 731.99 mi (1,178.03 km) |
| Great Wyrley to Striano | 1,128.60 mi (1,816.31 km) |
| Great Wyrley to Subiaco | 1,020.96 mi (1,643.08 km) |
| Great Wyrley to Sulmona | 1,041.55 mi (1,676.21 km) |
