| Grosse Pointe Park to Spello | 4,559.63 mi (7,338.01 km) |
| Grosse Pointe Park to Spilamberto | 4,430.27 mi (7,129.83 km) |
| Grosse Pointe Park to Spilimbergo | 4,440.98 mi (7,147.07 km) |
| Grosse Pointe Park to Spinea | 4,437.84 mi (7,142.01 km) |
| Grosse Pointe Park to Spoleto | 4,569.71 mi (7,354.24 km) |
| Grosse Pointe Park to Spoltore | 4,641.36 mi (7,469.55 km) |
| Grosse Pointe Park to Spresiano | 4,429.82 mi (7,129.10 km) |
| Grosse Pointe Park to Squinzano | 4,886.74 mi (7,864.45 km) |
| Grosse Pointe Park to Statte | 4,846.45 mi (7,799.61 km) |
| Grosse Pointe Park to Stezzano | 4,331.74 mi (6,971.26 km) |
| Grosse Pointe Park to Strada | 4,480.33 mi (7,210.39 km) |
| Grosse Pointe Park to Stradella | 4,339.38 mi (6,983.56 km) |
| Grosse Pointe Park to Striano | 4,727.99 mi (7,608.97 km) |
| Grosse Pointe Park to Subiaco | 4,620.70 mi (7,436.29 km) |
| Grosse Pointe Park to Sulmona | 4,649.72 mi (7,483.00 km) |
