| Grosse Pointe Park to Nuth | 3,993.65 mi (6,427.16 km) |
| Grosse Pointe Park to Oegstgeest | 3,898.46 mi (6,273.96 km) |
| Grosse Pointe Park to Oirschot | 3,952.08 mi (6,360.25 km) |
| Grosse Pointe Park to Oisterwijk | 3,945.56 mi (6,349.76 km) |
| Grosse Pointe Park to Oldebroek | 3,943.25 mi (6,346.05 km) |
| Grosse Pointe Park to Oldenzaal | 3,985.89 mi (6,414.67 km) |
| Grosse Pointe Park to Ommen | 3,960.16 mi (6,373.25 km) |
| Grosse Pointe Park to Oosterend | 3,931.27 mi (6,326.77 km) |
| Grosse Pointe Park to Oosterhout | 3,930.64 mi (6,325.75 km) |
| Grosse Pointe Park to Oosterwolde | 3,939.95 mi (6,340.74 km) |
| Grosse Pointe Park to Oostzaan | 3,906.01 mi (6,286.11 km) |
| Grosse Pointe Park to Opmeer | 3,899.92 mi (6,276.32 km) |
| Grosse Pointe Park to Oss | 3,951.44 mi (6,359.23 km) |
| Grosse Pointe Park to Oud-Beijerland | 3,907.74 mi (6,288.90 km) |
| Grosse Pointe Park to Oudenbosch | 3,919.79 mi (6,308.30 km) |
