| Grosse Pointe Park to Sangeorgiu de Mures | 4,855.75 mi (7,814.57 km) |
| Grosse Pointe Park to Sangeorz-Bai | 4,825.77 mi (7,766.33 km) |
| Grosse Pointe Park to Sannicolau Mare | 4,737.70 mi (7,624.60 km) |
| Grosse Pointe Park to Santana | 4,757.71 mi (7,656.79 km) |
| Grosse Pointe Park to Satu Mare | 4,743.68 mi (7,634.22 km) |
| Grosse Pointe Park to Scobinti | 4,903.44 mi (7,891.33 km) |
| Grosse Pointe Park to Scornicesti | 4,949.92 mi (7,966.13 km) |
| Grosse Pointe Park to Sebes | 4,850.51 mi (7,806.14 km) |
| Grosse Pointe Park to Seini | 4,759.55 mi (7,659.76 km) |
| Grosse Pointe Park to Sfantu-Gheorghe | 4,934.42 mi (7,941.18 km) |
| Grosse Pointe Park to Sibiu | 4,879.15 mi (7,852.24 km) |
| Grosse Pointe Park to Sighetu Marmatiei | 4,772.78 mi (7,681.05 km) |
| Grosse Pointe Park to Sighisoara | 4,882.60 mi (7,857.78 km) |
| Grosse Pointe Park to Simeria | 4,835.19 mi (7,781.48 km) |
| Grosse Pointe Park to Sinaia | 4,949.93 mi (7,966.15 km) |
