| Grosse Pointe Woods to Sacile | 4,428.65 mi (7,127.22 km) |
| Grosse Pointe Woods to Sala Consilina | 4,784.79 mi (7,700.37 km) |
| Grosse Pointe Woods to Salemi | 4,778.17 mi (7,689.71 km) |
| Grosse Pointe Woods to Salerno | 4,738.18 mi (7,625.36 km) |
| Grosse Pointe Woods to Salo | 4,365.29 mi (7,025.25 km) |
| Grosse Pointe Woods to Salsomaggiore Terme | 4,373.68 mi (7,038.75 km) |
| Grosse Pointe Woods to Saluzzo | 4,278.69 mi (6,885.89 km) |
| Grosse Pointe Woods to Salzano | 4,430.82 mi (7,130.71 km) |
| Grosse Pointe Woods to Samarate | 4,294.44 mi (6,911.24 km) |
| Grosse Pointe Woods to San Benedetto del Tronto | 4,606.69 mi (7,413.75 km) |
| Grosse Pointe Woods to San Biagio di Callalta | 4,435.16 mi (7,137.69 km) |
| Grosse Pointe Woods to San Bonifacio | 4,403.03 mi (7,085.99 km) |
| Grosse Pointe Woods to San Casciano in Val di Pesa | 4,468.44 mi (7,191.26 km) |
| Grosse Pointe Woods to San Cataldo | 4,843.16 mi (7,794.32 km) |
| Grosse Pointe Woods to San Cesareo | 4,609.63 mi (7,418.49 km) |
