| Grosse Pointe Woods to Sangeorgiu de Mures | 4,851.85 mi (7,808.30 km) |
| Grosse Pointe Woods to Sangeorz-Bai | 4,821.85 mi (7,760.02 km) |
| Grosse Pointe Woods to Sannicolau Mare | 4,733.87 mi (7,618.43 km) |
| Grosse Pointe Woods to Santana | 4,753.85 mi (7,650.59 km) |
| Grosse Pointe Woods to Satu Mare | 4,739.78 mi (7,627.93 km) |
| Grosse Pointe Woods to Scobinti | 4,899.49 mi (7,884.97 km) |
| Grosse Pointe Woods to Scornicesti | 4,946.07 mi (7,959.93 km) |
| Grosse Pointe Woods to Sebes | 4,846.64 mi (7,799.91 km) |
| Grosse Pointe Woods to Seini | 4,755.64 mi (7,653.47 km) |
| Grosse Pointe Woods to Sfantu-Gheorghe | 4,930.52 mi (7,934.90 km) |
| Grosse Pointe Woods to Sibiu | 4,875.28 mi (7,846.00 km) |
| Grosse Pointe Woods to Sighetu Marmatiei | 4,768.86 mi (7,674.74 km) |
| Grosse Pointe Woods to Sighisoara | 4,878.70 mi (7,851.51 km) |
| Grosse Pointe Woods to Simeria | 4,831.33 mi (7,775.27 km) |
| Grosse Pointe Woods to Sinaia | 4,946.05 mi (7,959.89 km) |
