| Guadalajara to Orbetello | 753.15 mi (1,212.08 km) |
| Guadalajara to Oria | 1,089.24 mi (1,752.97 km) |
| Guadalajara to Oristano | 621.49 mi (1,000.19 km) |
| Guadalajara to Orta Nova | 983.94 mi (1,583.50 km) |
| Guadalajara to Orte | 812.93 mi (1,308.28 km) |
| Guadalajara to Ortona | 915.22 mi (1,472.90 km) |
| Guadalajara to Orvieto | 800.32 mi (1,287.99 km) |
| Guadalajara to Orzinuovi | 738.01 mi (1,187.71 km) |
| Guadalajara to Osimo | 874.95 mi (1,408.09 km) |
| Guadalajara to Ospitaletto | 748.33 mi (1,204.32 km) |
| Guadalajara to Ostuni | 1,084.71 mi (1,745.67 km) |
| Guadalajara to Ottaviano | 922.25 mi (1,484.22 km) |
| Guadalajara to Ovada | 660.36 mi (1,062.75 km) |
| Guadalajara to Ozieri | 637.89 mi (1,026.59 km) |
| Guadalajara to Paceco | 858.73 mi (1,381.99 km) |
