| Guadalajara to Sacile | 867.74 mi (1,396.49 km) |
| Guadalajara to Sala Consilina | 984.03 mi (1,583.65 km) |
| Guadalajara to Salemi | 875.19 mi (1,408.48 km) |
| Guadalajara to Salerno | 938.03 mi (1,509.62 km) |
| Guadalajara to Salo | 770.11 mi (1,239.38 km) |
| Guadalajara to Salsomaggiore Terme | 726.06 mi (1,168.47 km) |
| Guadalajara to Saluzzo | 607.84 mi (978.22 km) |
| Guadalajara to Salzano | 840.54 mi (1,352.72 km) |
| Guadalajara to Samarate | 693.03 mi (1,115.32 km) |
| Guadalajara to San Benedetto del Tronto | 891.19 mi (1,434.23 km) |
| Guadalajara to San Biagio di Callalta | 856.04 mi (1,377.66 km) |
| Guadalajara to San Bonifacio | 799.34 mi (1,286.42 km) |
| Guadalajara to San Casciano in Val di Pesa | 763.27 mi (1,228.37 km) |
| Guadalajara to San Cataldo | 943.88 mi (1,519.03 km) |
| Guadalajara to San Cesareo | 832.58 mi (1,339.90 km) |
