| Guadalajara to Santa Venerina | 999.48 mi (1,608.50 km) |
| Guadalajara to Santeramo in Colle | 1,041.73 mi (1,676.50 km) |
| Guadalajara to Santo Stefano di Magra | 709.69 mi (1,142.13 km) |
| Guadalajara to Santo Stino di Livenza | 870.87 mi (1,401.53 km) |
| Guadalajara to Sarezzo | 756.48 mi (1,217.44 km) |
| Guadalajara to Sarno | 929.70 mi (1,496.21 km) |
| Guadalajara to Saronno | 704.37 mi (1,133.58 km) |
| Guadalajara to Sarzana | 710.94 mi (1,144.14 km) |
| Guadalajara to Sassari | 614.02 mi (988.17 km) |
| Guadalajara to Sasso Marconi | 777.71 mi (1,251.61 km) |
| Guadalajara to Sassuolo | 758.39 mi (1,220.51 km) |
| Guadalajara to Sava | 1,086.66 mi (1,748.82 km) |
| Guadalajara to Saviano | 923.91 mi (1,486.89 km) |
| Guadalajara to Savigliano | 614.41 mi (988.80 km) |
| Guadalajara to Savignano sul Panaro | 768.86 mi (1,237.37 km) |
