| Guadalajara to Santarem | 307.90 mi (495.51 km) |
| Guadalajara to Santiago do Cacem | 346.50 mi (557.64 km) |
| Guadalajara to Santo Andre | 347.54 mi (559.31 km) |
| Guadalajara to Santo Tirso | 280.55 mi (451.50 km) |
| Guadalajara to Sao Bras de Alportel | 349.54 mi (562.54 km) |
| Guadalajara to Sao Felix da Marinha | 286.49 mi (461.06 km) |
| Guadalajara to Sao Joao da Madeira | 279.03 mi (449.05 km) |
| Guadalajara to Sao Joao de Ver | 282.43 mi (454.53 km) |
| Guadalajara to Sao Mamede de Infesta | 286.28 mi (460.72 km) |
| Guadalajara to Sao Pedro do Sul | 256.76 mi (413.21 km) |
| Guadalajara to Satao | 239.30 mi (385.12 km) |
| Guadalajara to Seia | 238.59 mi (383.97 km) |
| Guadalajara to Senhora da Hora | 288.82 mi (464.81 km) |
| Guadalajara to Serpa | 301.06 mi (484.50 km) |
| Guadalajara to Serta | 266.50 mi (428.90 km) |
