| Guadalajara to Sesimbra | 350.34 mi (563.82 km) |
| Guadalajara to Setubal | 337.84 mi (543.70 km) |
| Guadalajara to Sever do Vouga | 272.46 mi (438.49 km) |
| Guadalajara to Silves | 370.06 mi (595.56 km) |
| Guadalajara to Sines | 356.34 mi (573.48 km) |
| Guadalajara to Sintra | 353.99 mi (569.69 km) |
| Guadalajara to Sobrado de Paiva | 267.96 mi (431.24 km) |
| Guadalajara to Sobral de Monte Agraco | 336.53 mi (541.59 km) |
| Guadalajara to Soure | 290.61 mi (467.69 km) |
| Guadalajara to Tabua | 256.11 mi (412.17 km) |
| Guadalajara to Tavira | 342.23 mi (550.77 km) |
| Guadalajara to Tomar | 286.36 mi (460.85 km) |
| Guadalajara to Tondela | 258.08 mi (415.34 km) |
| Guadalajara to Torre de Moncorvo | 210.71 mi (339.10 km) |
| Guadalajara to Torres Novas | 294.98 mi (474.72 km) |
