| Guadalajara to Sestao | 185.16 mi (297.98 km) |
| Guadalajara to Sevilla | 279.23 mi (449.38 km) |
| Guadalajara to Sevilla La Nueva | 49.38 mi (79.48 km) |
| Guadalajara to Silla | 170.34 mi (274.13 km) |
| Guadalajara to Silleda | 297.84 mi (479.32 km) |
| Guadalajara to Sitges | 262.76 mi (422.87 km) |
| Guadalajara to Socuellamos | 94.70 mi (152.40 km) |
| Guadalajara to Soller | 315.32 mi (507.45 km) |
| Guadalajara to Solsona | 260.64 mi (419.46 km) |
| Guadalajara to Son Servera | 351.78 mi (566.14 km) |
| Guadalajara to Sonseca | 76.61 mi (123.29 km) |
| Guadalajara to Sopelana | 190.09 mi (305.93 km) |
| Guadalajara to Soria | 86.34 mi (138.95 km) |
| Guadalajara to Suances | 198.66 mi (319.72 km) |
| Guadalajara to Sueca | 180.78 mi (290.93 km) |
