| Guadarrama to Savignano sul Rubicone | 872.00 mi (1,403.35 km) |
| Guadarrama to Savona | 687.01 mi (1,105.64 km) |
| Guadarrama to Scafati | 973.04 mi (1,565.95 km) |
| Guadarrama to Scalea | 1,048.33 mi (1,687.13 km) |
| Guadarrama to Scandiano | 797.08 mi (1,282.78 km) |
| Guadarrama to Scandicci | 808.99 mi (1,301.94 km) |
| Guadarrama to Schio | 850.48 mi (1,368.71 km) |
| Guadarrama to Sciacca | 945.08 mi (1,520.96 km) |
| Guadarrama to Scicli | 1,045.45 mi (1,682.49 km) |
| Guadarrama to Scordia | 1,041.26 mi (1,675.75 km) |
| Guadarrama to Scorze | 882.21 mi (1,419.78 km) |
| Guadarrama to Sedico | 893.41 mi (1,437.80 km) |
| Guadarrama to Sedriano | 736.75 mi (1,185.68 km) |
| Guadarrama to Segni | 890.83 mi (1,433.65 km) |
| Guadarrama to Segrate | 751.69 mi (1,209.73 km) |
