| Guadarrama to Sestu | 703.52 mi (1,132.20 km) |
| Guadarrama to Settimo Torinese | 673.62 mi (1,084.09 km) |
| Guadarrama to Seveso | 748.60 mi (1,204.75 km) |
| Guadarrama to Sezze | 893.77 mi (1,438.38 km) |
| Guadarrama to Siano | 981.50 mi (1,579.58 km) |
| Guadarrama to Siena | 811.37 mi (1,305.78 km) |
| Guadarrama to Signa | 804.95 mi (1,295.44 km) |
| Guadarrama to Silea | 892.55 mi (1,436.43 km) |
| Guadarrama to Silvi Paese | 947.50 mi (1,524.86 km) |
| Guadarrama to Sinalunga | 830.54 mi (1,336.63 km) |
| Guadarrama to Siniscola | 722.21 mi (1,162.29 km) |
| Guadarrama to Sinnai | 709.29 mi (1,141.50 km) |
| Guadarrama to Siracusa | 1,069.24 mi (1,720.77 km) |
| Guadarrama to Solaro | 745.46 mi (1,199.70 km) |
| Guadarrama to Soliera | 810.90 mi (1,305.02 km) |
