| Guadix to Spello | 920.73 mi (1,481.76 km) |
| Guadix to Spilamberto | 889.96 mi (1,432.25 km) |
| Guadix to Spilimbergo | 1,023.75 mi (1,647.56 km) |
| Guadix to Spinea | 971.39 mi (1,563.31 km) |
| Guadix to Spoleto | 916.01 mi (1,474.17 km) |
| Guadix to Spoltore | 980.47 mi (1,577.92 km) |
| Guadix to Spresiano | 985.33 mi (1,585.74 km) |
| Guadix to Squinzano | 1,157.03 mi (1,862.06 km) |
| Guadix to Statte | 1,113.24 mi (1,791.58 km) |
| Guadix to Stezzano | 876.15 mi (1,410.02 km) |
| Guadix to Strada | 873.33 mi (1,405.49 km) |
| Guadix to Stradella | 839.20 mi (1,350.57 km) |
| Guadix to Striano | 978.33 mi (1,574.47 km) |
| Guadix to Subiaco | 919.63 mi (1,480.00 km) |
| Guadix to Sulmona | 962.68 mi (1,549.29 km) |
