| Hard to Santeramo in Colle | 579.74 mi (933.01 km) |
| Hard to Santo Stefano di Magra | 230.11 mi (370.32 km) |
| Hard to Santo Stino di Livenza | 186.80 mi (300.62 km) |
| Hard to Sarezzo | 129.36 mi (208.19 km) |
| Hard to Sarno | 521.46 mi (839.20 km) |
| Hard to Saronno | 132.45 mi (213.16 km) |
| Hard to Sarzana | 233.59 mi (375.93 km) |
| Hard to Sassari | 470.58 mi (757.33 km) |
| Hard to Sasso Marconi | 226.21 mi (364.04 km) |
| Hard to Sassuolo | 209.65 mi (337.40 km) |
| Hard to Sava | 626.57 mi (1,008.36 km) |
| Hard to Saviano | 512.95 mi (825.52 km) |
| Hard to Savigliano | 219.53 mi (353.30 km) |
| Hard to Savignano sul Panaro | 217.46 mi (349.97 km) |
| Hard to Savignano sul Rubicone | 268.63 mi (432.32 km) |
