| Boston (Massachusetts) to Defiance | 687.08 mi (1,105.75 km) |
| Dallas (Texas) to Defiance | 899.30 mi (1,447.28 km) |
| Tampa (Florida) to Defiance | 924.43 mi (1,487.73 km) |
| Houston (Texas) to Defiance | 1,005.62 mi (1,618.39 km) |
| Denver (Colorado) to Defiance | 1,079.80 mi (1,737.77 km) |
| Miami (Florida) to Defiance | 1,096.81 mi (1,765.14 km) |
| Detroit (Michigan) to Defiance | 100.14 mi (161.16 km) |
| Phoenix (Arizona) to Defiance | 1,603.47 mi (2,580.54 km) |
| Las Vegas (Nevada) to Defiance | 1,691.57 mi (2,722.33 km) |
| Chicago (Illinois) to Defiance | 175.93 mi (283.13 km) |
| Riverside (California) to Defiance | 1,865.20 mi (3,001.75 km) |
| San Diego (California) to Defiance | 1,885.27 mi (3,034.05 km) |
| Seattle (Washington) to Defiance | 1,902.45 mi (3,061.70 km) |
| Los Angeles (California) to Defiance | 1,912.39 mi (3,077.69 km) |
| Portland (Oregon) to Defiance | 1,925.34 mi (3,098.54 km) |
| San Francisco (California) to Defiance | 2,027.82 mi (3,263.46 km) |
| St. Louis (Missouri) to Defiance | 360.94 mi (580.87 km) |
| Washington (District of Columbia) to Defiance | 421.56 mi (678.44 km) |
| Baltimore (Maryland) to Defiance | 430.53 mi (692.87 km) |
| Philadelphia (Pennsylvania) to Defiance | 491.67 mi (791.26 km) |
| Minneapolis (Minnesota) to Defiance | 515.59 mi (829.76 km) |
| Atlanta (Georgia) to Defiance | 519.49 mi (836.03 km) |
| Brooklyn (New York) to Defiance | 544.85 mi (876.85 km) |
| New York (New York) to Defiance | 545.72 mi (878.25 km) |
| Queens (New York) to Defiance | 551.83 mi (888.08 km) |
