| Hemel Hempstead to Sacile | 710.68 mi (1,143.74 km) |
| Hemel Hempstead to Sala Consilina | 1,094.63 mi (1,761.64 km) |
| Hemel Hempstead to Salemi | 1,158.16 mi (1,863.88 km) |
| Hemel Hempstead to Salerno | 1,051.96 mi (1,692.97 km) |
| Hemel Hempstead to Salo | 656.56 mi (1,056.63 km) |
| Hemel Hempstead to Salsomaggiore Terme | 677.40 mi (1,090.17 km) |
| Hemel Hempstead to Saluzzo | 612.04 mi (984.98 km) |
| Hemel Hempstead to Salzano | 715.87 mi (1,152.09 km) |
| Hemel Hempstead to Samarate | 597.34 mi (961.33 km) |
| Hemel Hempstead to San Benedetto del Tronto | 903.32 mi (1,453.75 km) |
| Hemel Hempstead to San Biagio di Callalta | 718.62 mi (1,156.51 km) |
| Hemel Hempstead to San Bonifacio | 692.30 mi (1,114.16 km) |
| Hemel Hempstead to San Casciano in Val di Pesa | 777.01 mi (1,250.47 km) |
| Hemel Hempstead to San Cataldo | 1,210.64 mi (1,948.33 km) |
| Hemel Hempstead to San Cesareo | 927.42 mi (1,492.54 km) |
