| Highgate to Shotley Bridge | 238.67 mi (384.10 km) |
| Highgate to Shrewsbury | 135.66 mi (218.32 km) |
| Highgate to Sidcup | 14.62 mi (23.53 km) |
| Highgate to Sidmouth | 147.63 mi (237.58 km) |
| Highgate to Sileby | 89.87 mi (144.64 km) |
| Highgate to Sittingbourne | 41.32 mi (66.49 km) |
| Highgate to Skegness | 110.55 mi (177.91 km) |
| Highgate to Skelmersdale | 175.76 mi (282.86 km) |
| Highgate to Skipton | 182.77 mi (294.14 km) |
| Highgate to Sleaford | 99.07 mi (159.43 km) |
| Highgate to Slough | 19.54 mi (31.45 km) |
| Highgate to Small Heath | 95.26 mi (153.31 km) |
| Highgate to Smethwick | 100.31 mi (161.44 km) |
| Highgate to Snaresbrook | 6.93 mi (11.15 km) |
| Highgate to Snodland | 30.53 mi (49.13 km) |
