| Highland Springs to Elyria (Ohio) | 366.99 mi (590.61 km) |
| Highland Springs to Emeryville (California) | 2,433.93 mi (3,917.04 km) |
| Highland Springs to Emmaus (Pennsylvania) | 228.34 mi (367.48 km) |
| Highland Springs to Emporia (Kansas) | 1,027.32 mi (1,653.31 km) |
| Highland Springs to Encinitas (California) | 2,256.16 mi (3,630.94 km) |
| Highland Springs to Endicott (New York) | 321.20 mi (516.92 km) |
| Highland Springs to Endwell (New York) | 323.05 mi (519.90 km) |
| Highland Springs to Englewood (Colorado) | 1,494.96 mi (2,405.91 km) |
| Highland Springs to Englewood (Florida) | 787.38 mi (1,267.17 km) |
| Highland Springs to Englewood (New Jersey) | 292.36 mi (470.51 km) |
| Highland Springs to Englewood (Ohio) | 408.63 mi (657.62 km) |
| Highland Springs to Enid (Oklahoma) | 1,134.30 mi (1,825.48 km) |
| Highland Springs to Ennis (Texas) | 1,149.08 mi (1,849.26 km) |
| Highland Springs to Ensley (Florida) | 747.41 mi (1,202.84 km) |
| Highland Springs to Enterprise (Alabama) | 647.94 mi (1,042.75 km) |
