| Highland Springs to Enterprise (Nevada) | 2,085.80 mi (3,356.78 km) |
| Highland Springs to Enumclaw (Washington) | 2,340.01 mi (3,765.89 km) |
| Highland Springs to Ephrata (Pennsylvania) | 191.87 mi (308.79 km) |
| Highland Springs to Erie (Colorado) | 1,496.04 mi (2,407.65 km) |
| Highland Springs to Erie (Pennsylvania) | 347.36 mi (559.03 km) |
| Highland Springs to Erlanger (Kentucky) | 406.23 mi (653.76 km) |
| Highland Springs to Escanaba (Michigan) | 756.93 mi (1,218.16 km) |
| Highland Springs to Escondido (California) | 2,243.89 mi (3,611.20 km) |
| Highland Springs to Española (New Mexico) | 1,587.91 mi (2,555.50 km) |
| Highland Springs to Essex (Maryland) | 130.06 mi (209.31 km) |
| Highland Springs to Essex Junction (Vermont) | 527.16 mi (848.38 km) |
| Highland Springs to Estelle (Louisiana) | 905.60 mi (1,457.43 km) |
| Highland Springs to Estero (Florida) | 811.65 mi (1,306.22 km) |
| Highland Springs to Euclid (Ohio) | 357.21 mi (574.88 km) |
| Highland Springs to Eufaula (Alabama) | 590.53 mi (950.36 km) |
