| Highland Springs to Scottsboro (Alabama) | 526.41 mi (847.17 km) |
| Highland Springs to Scottsdale (Arizona) | 1,947.05 mi (3,133.48 km) |
| Highland Springs to Scranton (Pennsylvania) | 280.58 mi (451.55 km) |
| Highland Springs to Seabrook (Maryland) | 102.06 mi (164.25 km) |
| Highland Springs to Seabrook (Texas) | 1,155.50 mi (1,859.60 km) |
| Highland Springs to Seaford (New York) | 297.69 mi (479.09 km) |
| Highland Springs to Seagoville (Texas) | 1,135.39 mi (1,827.23 km) |
| Highland Springs to Seal Beach (California) | 2,284.56 mi (3,676.64 km) |
| Highland Springs to Searcy (Arkansas) | 816.09 mi (1,313.37 km) |
| Highland Springs to Seaside (California) | 2,429.79 mi (3,910.37 km) |
| Highland Springs to SeaTac (Washington) | 2,354.49 mi (3,789.18 km) |
| Highland Springs to Seattle (Washington) | 2,355.74 mi (3,791.20 km) |
| Highland Springs to Sebastian (Florida) | 699.34 mi (1,125.48 km) |
| Highland Springs to Sebring (Florida) | 736.17 mi (1,184.75 km) |
| Highland Springs to Secaucus (New Jersey) | 283.38 mi (456.06 km) |
