| Highland Springs to Storm Lake (Iowa) | 1,005.34 mi (1,617.94 km) |
| Highland Springs to Storrs (Connecticut) | 399.08 mi (642.26 km) |
| Highland Springs to Stoughton (Wisconsin) | 727.89 mi (1,171.42 km) |
| Highland Springs to Stow (Ohio) | 332.83 mi (535.64 km) |
| Highland Springs to Streamwood (Illinois) | 652.88 mi (1,050.71 km) |
| Highland Springs to Streator (Illinois) | 661.66 mi (1,064.84 km) |
| Highland Springs to Streetsboro (Ohio) | 332.99 mi (535.89 km) |
| Highland Springs to Strongsville (Ohio) | 353.84 mi (569.45 km) |
| Highland Springs to Stuart (Florida) | 735.34 mi (1,183.42 km) |
| Highland Springs to Stuarts Draft (Virginia) | 98.64 mi (158.74 km) |
| Highland Springs to Sturgis (Michigan) | 520.41 mi (837.52 km) |
| Highland Springs to Suamico (Wisconsin) | 742.02 mi (1,194.17 km) |
| Highland Springs to Sudley (Virginia) | 85.90 mi (138.24 km) |
| Highland Springs to Suffern (New York) | 299.24 mi (481.57 km) |
| Highland Springs to Suffolk (Virginia) | 70.28 mi (113.11 km) |
