| Hilton Head Island to Savignano sul Rubicone | 4,856.32 mi (7,815.49 km) |
| Hilton Head Island to Savona | 4,674.25 mi (7,522.47 km) |
| Hilton Head Island to Scafati | 5,058.49 mi (8,140.85 km) |
| Hilton Head Island to Scalea | 5,148.55 mi (8,285.78 km) |
| Hilton Head Island to Scandiano | 4,765.26 mi (7,668.94 km) |
| Hilton Head Island to Scandicci | 4,812.46 mi (7,744.90 km) |
| Hilton Head Island to Schio | 4,762.10 mi (7,663.86 km) |
| Hilton Head Island to Sciacca | 5,097.30 mi (8,203.31 km) |
| Hilton Head Island to Scicli | 5,199.06 mi (8,367.08 km) |
| Hilton Head Island to Scordia | 5,188.91 mi (8,350.74 km) |
| Hilton Head Island to Scorze | 4,799.11 mi (7,723.43 km) |
| Hilton Head Island to Sedico | 4,782.58 mi (7,696.82 km) |
| Hilton Head Island to Sedriano | 4,663.34 mi (7,504.92 km) |
| Hilton Head Island to Segni | 4,959.18 mi (7,981.03 km) |
| Hilton Head Island to Segrate | 4,677.72 mi (7,528.07 km) |
