| Hilton Head Island to Selargius | 4,853.01 mi (7,810.16 km) |
| Hilton Head Island to Selvazzano Dentro | 4,790.46 mi (7,709.51 km) |
| Hilton Head Island to Senago | 4,667.95 mi (7,512.34 km) |
| Hilton Head Island to Senigallia | 4,904.63 mi (7,893.24 km) |
| Hilton Head Island to Seravezza | 4,762.15 mi (7,663.94 km) |
| Hilton Head Island to Seregno | 4,669.05 mi (7,514.10 km) |
| Hilton Head Island to Seriate | 4,690.94 mi (7,549.34 km) |
| Hilton Head Island to Sermoneta | 4,961.86 mi (7,985.35 km) |
| Hilton Head Island to Serramanna | 4,836.42 mi (7,783.47 km) |
| Hilton Head Island to Serravalle Pistoiese | 4,792.11 mi (7,712.15 km) |
| Hilton Head Island to Sessa Aurunca | 5,015.64 mi (8,071.90 km) |
| Hilton Head Island to Sesto Calende | 4,641.67 mi (7,470.05 km) |
| Hilton Head Island to Sesto Fiorentino | 4,810.58 mi (7,741.89 km) |
| Hilton Head Island to Sesto San Giovanni | 4,673.77 mi (7,521.70 km) |
| Hilton Head Island to Sestri Levante | 4,716.41 mi (7,590.34 km) |
