| Hilton Head Island to Spello | 4,902.61 mi (7,889.98 km) |
| Hilton Head Island to Spilamberto | 4,781.65 mi (7,695.33 km) |
| Hilton Head Island to Spilimbergo | 4,816.16 mi (7,750.86 km) |
| Hilton Head Island to Spinea | 4,803.72 mi (7,730.84 km) |
| Hilton Head Island to Spoleto | 4,910.42 mi (7,902.56 km) |
| Hilton Head Island to Spoltore | 4,985.73 mi (8,023.76 km) |
| Hilton Head Island to Spresiano | 4,798.97 mi (7,723.20 km) |
| Hilton Head Island to Squinzano | 5,230.53 mi (8,417.73 km) |
| Hilton Head Island to Statte | 5,187.27 mi (8,348.11 km) |
| Hilton Head Island to Stezzano | 4,689.03 mi (7,546.26 km) |
| Hilton Head Island to Strada | 4,823.31 mi (7,762.36 km) |
| Hilton Head Island to Stradella | 4,689.32 mi (7,546.74 km) |
| Hilton Head Island to Striano | 5,058.33 mi (8,140.59 km) |
| Hilton Head Island to Subiaco | 4,955.09 mi (7,974.45 km) |
| Hilton Head Island to Sulmona | 4,989.10 mi (8,029.18 km) |
