| Hilton Head Island to Sesimbra | 3,960.71 mi (6,374.14 km) |
| Hilton Head Island to Setubal | 3,969.72 mi (6,388.65 km) |
| Hilton Head Island to Sever do Vouga | 3,952.15 mi (6,360.37 km) |
| Hilton Head Island to Silves | 4,021.74 mi (6,472.37 km) |
| Hilton Head Island to Sines | 3,983.09 mi (6,410.17 km) |
| Hilton Head Island to Sintra | 3,938.55 mi (6,338.48 km) |
| Hilton Head Island to Sobrado de Paiva | 3,951.35 mi (6,359.09 km) |
| Hilton Head Island to Sobral de Monte Agraco | 3,946.27 mi (6,350.91 km) |
| Hilton Head Island to Soure | 3,952.10 mi (6,360.28 km) |
| Hilton Head Island to Tabua | 3,976.47 mi (6,399.52 km) |
| Hilton Head Island to Tavira | 4,064.46 mi (6,541.11 km) |
| Hilton Head Island to Tomar | 3,972.10 mi (6,392.47 km) |
| Hilton Head Island to Tondela | 3,970.65 mi (6,390.14 km) |
| Hilton Head Island to Torre de Moncorvo | 4,004.67 mi (6,444.90 km) |
| Hilton Head Island to Torres Novas | 3,968.85 mi (6,387.25 km) |
