| Hilton Head Island to Sangeorgiu de Mures | 5,283.45 mi (8,502.89 km) |
| Hilton Head Island to Sangeorz-Bai | 5,261.16 mi (8,467.02 km) |
| Hilton Head Island to Sannicolau Mare | 5,144.60 mi (8,279.44 km) |
| Hilton Head Island to Santana | 5,170.93 mi (8,321.81 km) |
| Hilton Head Island to Satu Mare | 5,175.11 mi (8,328.54 km) |
| Hilton Head Island to Scobinti | 5,348.50 mi (8,607.58 km) |
| Hilton Head Island to Scornicesti | 5,361.51 mi (8,628.51 km) |
| Hilton Head Island to Sebes | 5,269.36 mi (8,480.22 km) |
| Hilton Head Island to Seini | 5,192.26 mi (8,356.13 km) |
| Hilton Head Island to Sfantu-Gheorghe | 5,362.27 mi (8,629.75 km) |
| Hilton Head Island to Sibiu | 5,299.17 mi (8,528.18 km) |
| Hilton Head Island to Sighetu Marmatiei | 5,209.51 mi (8,383.89 km) |
| Hilton Head Island to Sighisoara | 5,308.95 mi (8,543.93 km) |
| Hilton Head Island to Simeria | 5,250.65 mi (8,450.11 km) |
| Hilton Head Island to Sinaia | 5,372.54 mi (8,646.26 km) |
