| Hilton Head Island to Santa Ursula | 3,784.40 mi (6,090.40 km) |
| Hilton Head Island to Santander | 4,121.77 mi (6,633.35 km) |
| Hilton Head Island to Santany | 4,556.45 mi (7,332.90 km) |
| Hilton Head Island to Santiago de Compostela | 3,903.43 mi (6,281.96 km) |
| Hilton Head Island to Santiago del Teide | 3,769.30 mi (6,066.11 km) |
| Hilton Head Island to Santiponce | 4,140.71 mi (6,663.83 km) |
| Hilton Head Island to Santomera | 4,381.39 mi (7,051.17 km) |
| Hilton Head Island to Santona | 4,138.85 mi (6,660.83 km) |
| Hilton Head Island to Santurce-Antiguo | 4,161.56 mi (6,697.39 km) |
| Hilton Head Island to Sarria | 3,960.27 mi (6,373.45 km) |
| Hilton Head Island to Sauzal | 3,786.22 mi (6,093.33 km) |
| Hilton Head Island to Sedavi | 4,380.60 mi (7,049.89 km) |
| Hilton Head Island to Segorbe | 4,364.90 mi (7,024.63 km) |
| Hilton Head Island to Segovia | 4,159.64 mi (6,694.30 km) |
| Hilton Head Island to Senmanat | 4,449.47 mi (7,160.74 km) |
