| Holbrook to Effingham (Illinois) | 826.90 mi (1,330.76 km) |
| Holbrook to Eggertsville (New York) | 330.97 mi (532.64 km) |
| Holbrook to Egypt Lake-Leto (Florida) | 1,032.26 mi (1,661.26 km) |
| Holbrook to El Cajon (California) | 2,463.58 mi (3,964.74 km) |
| Holbrook to El Campo (Texas) | 1,531.00 mi (2,463.90 km) |
| Holbrook to El Centro (California) | 2,390.77 mi (3,847.57 km) |
| Holbrook to El Cerrito (California) | 2,603.03 mi (4,189.17 km) |
| Holbrook to El Dorado (Arkansas) | 1,197.51 mi (1,927.21 km) |
| Holbrook to El Dorado (Kansas) | 1,284.32 mi (2,066.91 km) |
| Holbrook to El Dorado Hills (California) | 2,521.48 mi (4,057.93 km) |
| Holbrook to El Mirage (Arizona) | 2,198.02 mi (3,537.36 km) |
| Holbrook to El Monte (California) | 2,482.24 mi (3,994.78 km) |
| Holbrook to El Paso (Texas) | 1,943.65 mi (3,128.01 km) |
| Holbrook to El Paso de Robles (California) | 2,575.85 mi (4,145.43 km) |
| Holbrook to El Reno (Oklahoma) | 1,394.92 mi (2,244.91 km) |
