| Holbrook to Oswego (Illinois) | 794.55 mi (1,278.70 km) |
| Holbrook to Oswego (New York) | 254.15 mi (409.01 km) |
| Holbrook to Otsego (Minnesota) | 1,079.51 mi (1,737.31 km) |
| Holbrook to Ottawa (Illinois) | 820.46 mi (1,320.40 km) |
| Holbrook to Ottawa (Kansas) | 1,186.35 mi (1,909.24 km) |
| Holbrook to Ottumwa (Iowa) | 1,008.41 mi (1,622.88 km) |
| Holbrook to Overland (Missouri) | 928.80 mi (1,494.75 km) |
| Holbrook to Overland Park (Kansas) | 1,151.41 mi (1,853.02 km) |
| Holbrook to Overlea (Maryland) | 207.30 mi (333.62 km) |
| Holbrook to Oviedo (Florida) | 955.81 mi (1,538.22 km) |
| Holbrook to Owasso (Oklahoma) | 1,264.89 mi (2,035.64 km) |
| Holbrook to Owatonna (Minnesota) | 1,050.05 mi (1,689.88 km) |
| Holbrook to Owensboro (Kentucky) | 779.09 mi (1,253.82 km) |
| Holbrook to Owings Mills (Maryland) | 218.62 mi (351.84 km) |
| Holbrook to Owosso (Michigan) | 590.59 mi (950.46 km) |
