| Holly Springs to Sacile | 4,564.05 mi (7,345.13 km) |
| Holly Springs to Sala Consilina | 4,887.62 mi (7,865.86 km) |
| Holly Springs to Salemi | 4,849.21 mi (7,804.05 km) |
| Holly Springs to Salerno | 4,839.77 mi (7,788.86 km) |
| Holly Springs to Salo | 4,490.87 mi (7,227.35 km) |
| Holly Springs to Salsomaggiore Terme | 4,490.74 mi (7,227.15 km) |
| Holly Springs to Saluzzo | 4,385.68 mi (7,058.07 km) |
| Holly Springs to Salzano | 4,561.33 mi (7,340.75 km) |
| Holly Springs to Samarate | 4,414.21 mi (7,103.98 km) |
| Holly Springs to San Benedetto del Tronto | 4,722.74 mi (7,600.51 km) |
| Holly Springs to San Biagio di Callalta | 4,567.85 mi (7,351.24 km) |
| Holly Springs to San Bonifacio | 4,529.53 mi (7,289.58 km) |
| Holly Springs to San Casciano in Val di Pesa | 4,580.17 mi (7,371.07 km) |
| Holly Springs to San Cataldo | 4,916.65 mi (7,912.58 km) |
| Holly Springs to San Cesareo | 4,712.46 mi (7,583.98 km) |
