| Holtsville to Chicago (Illinois) | 762.09 mi (1,226.47 km) |
| Holtsville to Atlanta (Georgia) | 791.56 mi (1,273.90 km) |
| Holtsville to St. Louis (Missouri) | 924.79 mi (1,488.31 km) |
| Holtsville to Tampa (Florida) | 1,033.64 mi (1,663.48 km) |
| Holtsville to Minneapolis (Minnesota) | 1,060.03 mi (1,705.95 km) |
| Holtsville to Miami (Florida) | 1,116.74 mi (1,797.21 km) |
| Holtsville to Philadelphia (Pennsylvania) | 123.17 mi (198.22 km) |
| Holtsville to Dallas (Texas) | 1,418.75 mi (2,283.25 km) |
| Holtsville to Houston (Texas) | 1,465.90 mi (2,359.13 km) |
| Holtsville to Denver (Colorado) | 1,670.00 mi (2,687.60 km) |
| Holtsville to Boston (Massachusetts) | 145.23 mi (233.73 km) |
| Holtsville to Phoenix (Arizona) | 2,187.43 mi (3,520.33 km) |
| Holtsville to Las Vegas (Nevada) | 2,281.87 mi (3,672.32 km) |
| Holtsville to Seattle (Washington) | 2,442.64 mi (3,931.05 km) |
| Holtsville to Riverside (California) | 2,454.24 mi (3,949.72 km) |
| Holtsville to San Diego (California) | 2,472.44 mi (3,979.00 km) |
| Holtsville to Portland (Oregon) | 2,480.59 mi (3,992.13 km) |
| Holtsville to Los Angeles (California) | 2,502.03 mi (4,026.62 km) |
| Holtsville to San Francisco (California) | 2,615.29 mi (4,208.91 km) |
| Holtsville to Queens (New York) | 39.63 mi (63.77 km) |
| Holtsville to New York (New York) | 46.79 mi (75.30 km) |
| Holtsville to Brooklyn (New York) | 48.69 mi (78.35 km) |
| Holtsville to Baltimore (Maryland) | 215.57 mi (346.93 km) |
| Holtsville to Washington (District of Columbia) | 248.45 mi (399.84 km) |
| Holtsville to Detroit (Michigan) | 530.55 mi (853.84 km) |
