| Holyhead to Senftenberg | 793.33 mi (1,276.74 km) |
| Holyhead to Siegburg | 531.17 mi (854.84 km) |
| Holyhead to Siegen | 561.61 mi (903.82 km) |
| Holyhead to Sigmaringen | 703.63 mi (1,132.39 km) |
| Holyhead to Simbach am Inn | 843.09 mi (1,356.82 km) |
| Holyhead to Simmerath | 501.10 mi (806.45 km) |
| Holyhead to Sindelfingen | 670.93 mi (1,079.76 km) |
| Holyhead to Sinsheim | 646.63 mi (1,040.65 km) |
| Holyhead to Sinzheim | 637.42 mi (1,025.84 km) |
| Holyhead to Sinzig | 540.39 mi (869.68 km) |
| Holyhead to Soest | 549.15 mi (883.78 km) |
| Holyhead to Solingen | 516.68 mi (831.51 km) |
| Holyhead to Soltau | 598.89 mi (963.82 km) |
| Holyhead to Sommerda | 681.25 mi (1,096.36 km) |
| Holyhead to Sondershausen | 666.55 mi (1,072.70 km) |
