| Holyhead to Sonneberg | 703.26 mi (1,131.78 km) |
| Holyhead to Sonsbeck | 477.64 mi (768.69 km) |
| Holyhead to Sonthofen | 766.82 mi (1,234.07 km) |
| Holyhead to Spaichingen | 686.30 mi (1,104.49 km) |
| Holyhead to Spelle | 508.56 mi (818.45 km) |
| Holyhead to Spenge | 554.08 mi (891.70 km) |
| Holyhead to Speyer | 626.68 mi (1,008.55 km) |
| Holyhead to Spiesen-Elversberg | 577.20 mi (928.92 km) |
| Holyhead to Spremberg | 807.24 mi (1,299.13 km) |
| Holyhead to Springe | 596.76 mi (960.39 km) |
| Holyhead to Sprockhovel | 518.61 mi (834.62 km) |
| Holyhead to Stade | 579.89 mi (933.24 km) |
| Holyhead to Stadtallendorf | 603.34 mi (970.99 km) |
| Holyhead to Stadthagen | 580.98 mi (934.99 km) |
| Holyhead to Stadtlohn | 491.96 mi (791.73 km) |
