| Holyhead to Sierpc | 1,003.72 mi (1,615.34 km) |
| Holyhead to Skarzysko-Kamienna | 1,086.25 mi (1,748.15 km) |
| Holyhead to Skawina | 1,068.18 mi (1,719.07 km) |
| Holyhead to Skierniewice | 1,038.00 mi (1,670.49 km) |
| Holyhead to Skoczow | 1,029.88 mi (1,657.44 km) |
| Holyhead to Skwierzyna | 836.69 mi (1,346.52 km) |
| Holyhead to Slawno | 868.49 mi (1,397.70 km) |
| Holyhead to Slubice | 801.79 mi (1,290.36 km) |
| Holyhead to Slupca | 938.47 mi (1,510.32 km) |
| Holyhead to Slupsk | 882.21 mi (1,419.78 km) |
| Holyhead to Sochaczew | 1,036.82 mi (1,668.60 km) |
| Holyhead to Sokolka | 1,152.65 mi (1,855.00 km) |
| Holyhead to Sokolow Podlaski | 1,116.71 mi (1,797.17 km) |
| Holyhead to Solec Kujawski | 942.57 mi (1,516.92 km) |
| Holyhead to Sopot | 943.88 mi (1,519.02 km) |
