| Holyhead to El Astillero | 685.53 mi (1,103.26 km) |
| Holyhead to El Ejido | 1,145.17 mi (1,842.97 km) |
| Holyhead to El Escorial | 879.69 mi (1,415.73 km) |
| Holyhead to El Espinar | 870.10 mi (1,400.29 km) |
| Holyhead to El Molar | 870.26 mi (1,400.55 km) |
| Holyhead to El Prat de Llobregat | 885.03 mi (1,424.32 km) |
| Holyhead to El Puerto de Santa Maria | 1,157.00 mi (1,862.01 km) |
| Holyhead to El Viso del Alcor | 1,101.58 mi (1,772.83 km) |
| Holyhead to Elche | 1,056.04 mi (1,699.54 km) |
| Holyhead to Elda | 1,040.75 mi (1,674.92 km) |
| Holyhead to Elgoibar | 704.80 mi (1,134.27 km) |
| Holyhead to Erandio | 695.38 mi (1,119.10 km) |
| Holyhead to Ermua | 706.09 mi (1,136.34 km) |
| Holyhead to Esparraguera | 867.35 mi (1,395.86 km) |
| Holyhead to Espartinas | 1,102.65 mi (1,774.55 km) |
