| Holyhead to Sabadell | 870.58 mi (1,401.06 km) |
| Holyhead to Sabinanigo | 770.95 mi (1,240.72 km) |
| Holyhead to Sagunto | 964.02 mi (1,551.44 km) |
| Holyhead to Salamanca | 854.24 mi (1,374.77 km) |
| Holyhead to Salobrena | 1,145.45 mi (1,843.43 km) |
| Holyhead to Salou | 886.53 mi (1,426.73 km) |
| Holyhead to Salt | 854.75 mi (1,375.58 km) |
| Holyhead to Salvatierra de Mino | 795.89 mi (1,280.86 km) |
| Holyhead to Sama | 693.22 mi (1,115.62 km) |
| Holyhead to San Adrian de Besos | 880.13 mi (1,416.44 km) |
| Holyhead to San Agustin de Guadalix | 874.00 mi (1,406.57 km) |
| Holyhead to San Andres de la Barca | 875.02 mi (1,408.20 km) |
| Holyhead to San Andres de Llevaneras | 875.34 mi (1,408.73 km) |
| Holyhead to San Andres del Rabanedo | 740.10 mi (1,191.08 km) |
| Holyhead to San Bartolome | 1,840.44 mi (2,961.91 km) |
