| Holyhead to Domanic | 1,850.32 mi (2,977.80 km) |
| Holyhead to Duragan | 1,998.18 mi (3,215.77 km) |
| Holyhead to Duzce | 1,865.08 mi (3,001.56 km) |
| Holyhead to Eceabat | 1,704.59 mi (2,743.28 km) |
| Holyhead to Edirne | 1,644.41 mi (2,646.42 km) |
| Holyhead to Edremit | 1,758.19 mi (2,829.53 km) |
| Holyhead to Elazig | 2,288.93 mi (3,683.68 km) |
| Holyhead to Elbistan | 2,227.63 mi (3,585.02 km) |
| Holyhead to Eleskirt | 2,380.84 mi (3,831.60 km) |
| Holyhead to Emet | 1,858.24 mi (2,990.55 km) |
| Holyhead to Emirdag | 1,947.46 mi (3,134.14 km) |
| Holyhead to Emirgazi | 2,106.60 mi (3,390.25 km) |
| Holyhead to Enez | 1,667.83 mi (2,684.11 km) |
| Holyhead to Erbaa | 2,092.32 mi (3,367.27 km) |
| Holyhead to Ercis | 2,442.78 mi (3,931.27 km) |
