| Cities | Distance |
|---|---|
| Holyhead to Enniskillen | 141.92 mi (228.40 km) |
| Holyhead to Epping | 228.24 mi (367.31 km) |
| Holyhead to Epsom | 229.24 mi (368.92 km) |
| Holyhead to Erdington | 128.46 mi (206.74 km) |
| Holyhead to Erith | 238.90 mi (384.48 km) |
| Holyhead to Esher | 224.50 mi (361.30 km) |
| Holyhead to Euxton | 84.15 mi (135.42 km) |
| Holyhead to Evesham | 140.41 mi (225.96 km) |
| Holyhead to Evington | 155.61 mi (250.43 km) |
| Holyhead to Ewell | 229.25 mi (368.94 km) |
| Holyhead to Exeter | 184.58 mi (297.06 km) |
| Holyhead to Exmouth | 192.91 mi (310.45 km) |
| Holyhead to Failsworth | 102.89 mi (165.59 km) |
| Holyhead to Falkirk | 189.08 mi (304.29 km) |
| Holyhead to Falmouth | 219.06 mi (352.55 km) |