| Houston to Delaware (Ohio) | 1,003.79 mi (1,615.44 km) |
| Houston to Delhi (California) | 1,547.57 mi (2,490.57 km) |
| Houston to Delray Beach (Florida) | 959.37 mi (1,543.96 km) |
| Houston to Deltona (Florida) | 855.34 mi (1,376.53 km) |
| Houston to Deming (New Mexico) | 751.32 mi (1,209.13 km) |
| Houston to Denison (Texas) | 283.84 mi (456.80 km) |
| Houston to Dent (Ohio) | 890.63 mi (1,433.33 km) |
| Houston to Denton (Texas) | 258.60 mi (416.18 km) |
| Houston to Dentsville (South Carolina) | 895.77 mi (1,441.60 km) |
| Houston to Denver (Colorado) | 873.50 mi (1,405.77 km) |
| Houston to Depew (New York) | 1,293.23 mi (2,081.25 km) |
| Houston to Derby (Connecticut) | 1,479.02 mi (2,380.25 km) |
| Houston to Derby (Kansas) | 547.52 mi (881.14 km) |
| Houston to Des Moines (Iowa) | 820.40 mi (1,320.31 km) |
| Houston to Des Moines (Washington) | 1,878.94 mi (3,023.86 km) |
