| Houston to Des Plaines (Illinois) | 943.38 mi (1,518.23 km) |
| Houston to Desert Hot Springs (California) | 1,271.75 mi (2,046.69 km) |
| Houston to DeSoto (Texas) | 213.02 mi (342.82 km) |
| Houston to Destin (Florida) | 534.68 mi (860.48 km) |
| Houston to Destrehan (Louisiana) | 301.04 mi (484.47 km) |
| Houston to Detroit (Michigan) | 1,105.74 mi (1,779.52 km) |
| Houston to Diamond Bar (California) | 1,344.55 mi (2,163.84 km) |
| Houston to Diamond Springs (California) | 1,571.82 mi (2,529.60 km) |
| Houston to Dickinson (North Dakota) | 1,246.73 mi (2,006.42 km) |
| Houston to Dickinson (Texas) | 30.26 mi (48.70 km) |
| Houston to Dickson (Tennessee) | 635.60 mi (1,022.91 km) |
| Houston to Difficult Run (Virginia) | 1,203.25 mi (1,936.44 km) |
| Houston to Dinuba (California) | 1,460.45 mi (2,350.37 km) |
| Houston to Discovery Bay (California) | 1,598.66 mi (2,572.79 km) |
| Houston to Dix Hills (New York) | 1,451.70 mi (2,336.28 km) |
