| Houston to Elyria (Ohio) | 1,092.10 mi (1,757.56 km) |
| Houston to Emeryville (California) | 1,634.66 mi (2,630.72 km) |
| Houston to Emmaus (Pennsylvania) | 1,341.83 mi (2,159.47 km) |
| Houston to Emporia (Kansas) | 597.13 mi (960.99 km) |
| Houston to Encinitas (California) | 1,306.76 mi (2,103.02 km) |
| Houston to Endicott (New York) | 1,369.94 mi (2,204.70 km) |
| Houston to Endwell (New York) | 1,372.51 mi (2,208.84 km) |
| Houston to Englewood (Colorado) | 871.65 mi (1,402.79 km) |
| Houston to Englewood (Florida) | 815.45 mi (1,312.34 km) |
| Houston to Englewood (New Jersey) | 1,424.23 mi (2,292.08 km) |
| Houston to Englewood (Ohio) | 936.50 mi (1,507.15 km) |
| Houston to Enid (Oklahoma) | 479.39 mi (771.50 km) |
| Houston to Ennis (Texas) | 190.33 mi (306.30 km) |
| Houston to Ensley (Florida) | 487.40 mi (784.39 km) |
| Houston to Enterprise (Alabama) | 577.44 mi (929.31 km) |
