| Houston to Oswego (Illinois) | 911.39 mi (1,466.74 km) |
| Houston to Oswego (New York) | 1,404.01 mi (2,259.53 km) |
| Houston to Otsego (Minnesota) | 1,073.87 mi (1,728.23 km) |
| Houston to Ottawa (Illinois) | 879.66 mi (1,415.67 km) |
| Houston to Ottawa (Kansas) | 609.00 mi (980.09 km) |
| Houston to Ottumwa (Iowa) | 793.83 mi (1,277.55 km) |
| Houston to Overland (Missouri) | 678.84 mi (1,092.49 km) |
| Houston to Overland Park (Kansas) | 630.08 mi (1,014.02 km) |
| Houston to Overlea (Maryland) | 1,257.23 mi (2,023.32 km) |
| Houston to Oviedo (Florida) | 859.33 mi (1,382.96 km) |
| Houston to Owasso (Oklahoma) | 449.96 mi (724.14 km) |
| Houston to Owatonna (Minnesota) | 995.45 mi (1,602.02 km) |
| Houston to Owensboro (Kentucky) | 726.68 mi (1,169.47 km) |
| Houston to Owings Mills (Maryland) | 1,245.57 mi (2,004.55 km) |
| Houston to Owosso (Michigan) | 1,103.15 mi (1,775.34 km) |
