| Houston to Saddlebrooke (Arizona) | 934.36 mi (1,503.71 km) |
| Houston to Safety Harbor (Florida) | 777.10 mi (1,250.62 km) |
| Houston to Saginaw (Michigan) | 1,133.31 mi (1,823.88 km) |
| Houston to Saginaw (Texas) | 242.66 mi (390.53 km) |
| Houston to Sahuarita (Arizona) | 934.87 mi (1,504.52 km) |
| Houston to Saks (Alabama) | 622.06 mi (1,001.10 km) |
| Houston to Salem (Massachusetts) | 1,615.41 mi (2,599.75 km) |
| Houston to Salem (Ohio) | 1,120.32 mi (1,802.97 km) |
| Houston to Salem (Oregon) | 1,828.66 mi (2,942.94 km) |
| Houston to Salem (Virginia) | 1,021.93 mi (1,644.63 km) |
| Houston to Salem Lakes (Wisconsin) | 968.61 mi (1,558.83 km) |
| Houston to Salida (California) | 1,568.23 mi (2,523.83 km) |
| Houston to Salina (Kansas) | 636.49 mi (1,024.33 km) |
| Houston to Salinas (California) | 1,583.95 mi (2,549.12 km) |
| Houston to Salisbury (Maryland) | 1,275.38 mi (2,052.53 km) |
