| Houston to Salisbury (New York) | 1,439.43 mi (2,316.54 km) |
| Houston to Salisbury (North Carolina) | 955.10 mi (1,537.08 km) |
| Houston to Salmon Creek (Washington) | 1,837.06 mi (2,956.46 km) |
| Houston to Salt Lake City (Utah) | 1,199.42 mi (1,930.27 km) |
| Houston to Sammamish (Washington) | 1,875.48 mi (3,018.29 km) |
| Houston to San Angelo (Texas) | 321.97 mi (518.17 km) |
| Houston to San Anselmo (California) | 1,651.46 mi (2,657.77 km) |
| Houston to San Antonio (Texas) | 189.62 mi (305.17 km) |
| Houston to San Benito (Texas) | 287.67 mi (462.95 km) |
| Houston to San Bernardino (California) | 1,316.05 mi (2,117.97 km) |
| Houston to San Bruno (California) | 1,639.11 mi (2,637.89 km) |
| Houston to San Buenaventura (California) | 1,427.05 mi (2,296.62 km) |
| Houston to San Carlos (California) | 1,628.61 mi (2,620.99 km) |
| Houston to San Carlos Park (Florida) | 857.21 mi (1,379.54 km) |
| Houston to San Clemente (California) | 1,329.04 mi (2,138.89 km) |
