| Houston to San Luis Obispo (California) | 1,516.03 mi (2,439.82 km) |
| Houston to San Marcos (California) | 1,302.19 mi (2,095.67 km) |
| Houston to San Marcos (Texas) | 152.79 mi (245.89 km) |
| Houston to San Marino (California) | 1,362.40 mi (2,192.56 km) |
| Houston to San Mateo (California) | 1,631.72 mi (2,626.00 km) |
| Houston to San Pablo (California) | 1,639.08 mi (2,637.84 km) |
| Houston to San Rafael (California) | 1,649.04 mi (2,653.87 km) |
| Houston to San Ramon (California) | 1,614.52 mi (2,598.32 km) |
| Houston to San Tan Valley (Arizona) | 980.31 mi (1,577.66 km) |
| Houston to Sand Springs (Oklahoma) | 440.78 mi (709.37 km) |
| Houston to Sandusky (Ohio) | 1,073.17 mi (1,727.10 km) |
| Houston to Sandy (Oregon) | 1,810.28 mi (2,913.37 km) |
| Houston to Sandy (Utah) | 1,187.95 mi (1,911.82 km) |
| Houston to Sandy Springs (Georgia) | 706.79 mi (1,137.47 km) |
| Houston to Sanford (Florida) | 852.71 mi (1,372.30 km) |
