| Houston to Security-Widefield (Colorado) | 815.76 mi (1,312.85 km) |
| Houston to Sedalia (Missouri) | 628.41 mi (1,011.33 km) |
| Houston to Sedro-Woolley (Washington) | 1,916.27 mi (3,083.93 km) |
| Houston to Seguin (Texas) | 155.40 mi (250.09 km) |
| Houston to Selden (New York) | 1,467.49 mi (2,361.69 km) |
| Houston to Selma (Alabama) | 526.45 mi (847.24 km) |
| Houston to Selma (California) | 1,472.54 mi (2,369.82 km) |
| Houston to Selma (Texas) | 176.09 mi (283.39 km) |
| Houston to Seminole (Florida) | 774.35 mi (1,246.19 km) |
| Houston to Seven Hills (Ohio) | 1,108.85 mi (1,784.52 km) |
| Houston to Seven Oaks (South Carolina) | 884.84 mi (1,424.01 km) |
| Houston to Severn (Maryland) | 1,241.77 mi (1,998.44 km) |
| Houston to Severna Park (Maryland) | 1,246.47 mi (2,006.00 km) |
| Houston to Sevierville (Tennessee) | 804.44 mi (1,294.63 km) |
| Houston to Seymour (Indiana) | 832.09 mi (1,339.12 km) |
