| Houston to Seymour (Tennessee) | 794.35 mi (1,278.39 km) |
| Houston to Shady Hills (Florida) | 780.75 mi (1,256.50 km) |
| Houston to Shafter (California) | 1,436.29 mi (2,311.49 km) |
| Houston to Shaker Heights (Ohio) | 1,117.97 mi (1,799.20 km) |
| Houston to Shakopee (Minnesota) | 1,040.84 mi (1,675.07 km) |
| Houston to Sharon (Pennsylvania) | 1,148.74 mi (1,848.72 km) |
| Houston to Sharonville (Ohio) | 904.79 mi (1,456.12 km) |
| Houston to Shasta Lake (California) | 1,689.53 mi (2,719.04 km) |
| Houston to Shawnee (Kansas) | 638.57 mi (1,027.68 km) |
| Houston to Shawnee (Oklahoma) | 395.43 mi (636.38 km) |
| Houston to Sheboygan (Wisconsin) | 1,052.01 mi (1,693.05 km) |
| Houston to Shelby (North Carolina) | 890.40 mi (1,432.96 km) |
| Houston to Shelbyville (Indiana) | 866.02 mi (1,393.73 km) |
| Houston to Shelbyville (Kentucky) | 821.87 mi (1,322.66 km) |
| Houston to Shelbyville (Tennessee) | 652.29 mi (1,049.76 km) |
