| Houston to Superior (Colorado) | 892.32 mi (1,436.05 km) |
| Houston to Superior (Wisconsin) | 1,181.65 mi (1,901.68 km) |
| Houston to Surprise (Arizona) | 1,036.79 mi (1,668.55 km) |
| Houston to Susanville (California) | 1,596.08 mi (2,568.64 km) |
| Houston to Sussex (Wisconsin) | 1,003.61 mi (1,615.15 km) |
| Houston to Suwanee (Georgia) | 725.75 mi (1,167.98 km) |
| Houston to Swansea (Illinois) | 679.45 mi (1,093.47 km) |
| Houston to Sweetwater (Florida) | 957.68 mi (1,541.23 km) |
| Houston to Sweetwater (Texas) | 350.00 mi (563.27 km) |
| Houston to Sycamore (Illinois) | 922.58 mi (1,484.76 km) |
| Houston to Sylacauga (Alabama) | 586.40 mi (943.72 km) |
| Houston to Sylvania (Ohio) | 1,050.34 mi (1,690.36 km) |
| Houston to Syosset (New York) | 1,444.25 mi (2,324.30 km) |
| Houston to Syracuse (New York) | 1,402.30 mi (2,256.79 km) |
| Houston to Syracuse (Utah) | 1,217.41 mi (1,959.24 km) |
